Patients & Care Partners

Sage is pursuing new treatment pathways with the goal of improving brain health.

When everyone said brain health disorders were too tough to tackle, Sage said that they are too important not to. It’s why everything we do – from our journey of scientific discovery and development to our work with patients, care partners, and advocates – is laser-focused on our mission of making medicines that matter so people can get better, sooner.

Our depression, neurology and neuropsychiatry franchise programs aim to change how brain health disorders are thought about and treated.

Clinical Trials

We are conducting clinical trials in several brain health disorders where there is a need for additional treatment options to determine if our investigational medicines are safe and effective for patients living with those disorders.

The experiences of patients & care partners motivate us.


At Sage, identifying unmet patient needs drives our research and development focus. We seek to increase awareness and improve understanding of brain health disorders and integrate patient and care partner perspectives into every aspect of our work. Sage understands that brain health disorders affect not only individuals, but families, communities, and society. We engage with advocacy groups and those they serve to listen and learn from them as we rethink care and how to deliver it.

Expanded Access Program

We understand that, in some cases, patients with serious diseases or conditions may not be eligible for clinical trials and may not have other treatment options. Under very limited circumstances, we will consider making investigational medicines available for individual patients to treat a serious disease or condition outside of a clinical trial. “Expanded access” and “compassionate use” are terms that describe this type of access. For more information, see our Expanded Access Program description.