In 2020, an estimated 21 million adults in the U.S. experienced at least one major depressive episode in the past 12 months, and 500,000 people suffer from postpartum depression (PPD) every year. We invite you to explore how the Brain Works to see how changes in the brain due to MDD and PPD can influence behavior, and the performance of GABA receptors – a critical part of the neural system that helps balance the brain’s neural activity.

In the latest episode of Conversations – the podcast that brings you unique points of view on how we think about and treat brain health disorders – Mark Pollack, Senior Vice President of Global Medical Affairs for Sage, and Dr. Samantha Meltzer-Brody, MD, MPH, Chair of the UNC Department of Psychiatry and Director of the UNC Center for Women’s Mood Disorders, discuss the current depression management landscape, lived patient experience and the importance of partnering with clinicians for real-time insights.

As part of Mental Health Awareness Month, we are sharing Sheante B.’s story. In her own words, she describes her lived experience with Major Depressive Disorder (MDD) and shares an important lesson from her journey: it can get better.