Sage is a commercial-stage company with a track record of success that is a direct result of our approach to discovery and translation into the clinic and market. Our mission is to create and develop medicines that matter, so people can get better, sooner. Our GABA and NMDA research areas are just the beginning. We are actively seeking innovative opportunities with academia and industry.

Everyone said brain health disorders were too tough to tackle... we said they are too important not to.

At Sage, we:

  • think differently about brain health disorders and how we approach the discovery and development of new medicines.
  • search for solutions that have the potential to work faster and last longer, to radically—not just incrementally—improve the lives of patients and their families.
  • leverage our distinct approach to translational medicines and science to drive efficiency in our drug development approach.

We are pursuing new pathways with the goal of improving brain health. Our depression, neurology and neuropsychiatry franchise programs aim to change how brain health disorders are thought about and treated. Although brain health disorders are our primary focus, we may also evaluate opportunities in adjacent areas of interest. We are committed to growing our portfolio, starting with a robust R&D process evaluating the safety and efficacy of our novel drug candidates with the goal of potentially addressing gaps in available treatment options for debilitating brain health disorders. To rapidly advance our clinical development programs, we design efficient studies to look for profound therapeutic effects, and partnered opportunities will be developed using the same principles.

Partnership Focus at Sage

With our distinct approach to discovering and developing new medicines, we have built a pipeline of differentiated assets.

We are interested in exploring strategic partnerships that:

Complement our GABA Platform

We’ve built tremendous capabilities around the GABA research area, and believe more is out there.

Expand on our NMDA Platform

We see great promise in the NMDA research and are interested in exploring opportunistic ways to augment the innovative work we have already done.

Introduce Novel Mechanisms of Action

Our team is driven to create first-in-class or best-in-class medicines with the potential to get patients better, sooner.

Our commitment to growing our portfolio includes evaluating opportunities that meet the following criteria:

  • Asset stage: preclinical through commercial
  • Modality: small molecules are preferred, but we may be opportunistic on biologics with compelling data
  • Indications: most brain health disorders representing clear unmet medical needs

Current Partnerships